H. J. Muller
Hermann Joseph Muller (December 21, 1890 – April 5, 1967) was an American geneticist, educator, and Nobel laureate best known for his work on the physiological and genetic effects of radiation ( mutagenesis), as well as his outspoken political beliefs. Muller frequently warned of long-term dangers of radioactive fallout from nuclear war and nuclear testing, which resulted in greater public scrutiny of these practices. Early life Muller was born in New York City, the son of Frances (Lyons) and Hermann Joseph Muller Sr., an artisan who worked with metals. Muller was a third-generation American whose father's ancestors were originally Catholic and came to the United States from Koblenz. His mother's family was of mixed Jewish (descended from Spanish and Portuguese Jews) and Anglican background, and had come from Britain. Among his first cousins are Herbert J. Muller and Alfred Kroeber (Kroeber is Ursula Le Guin's father). As an adolescent, Muller attended a Unitarian church ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Indianapolis, Indiana
Indianapolis (), colloquially known as Indy, is the state capital and most populous city of the U.S. state of Indiana and the seat of Marion County. According to the U.S. Census Bureau, the consolidated population of Indianapolis and Marion County was 977,203 in 2020. The "balance" population, which excludes semi-autonomous municipalities in Marion County, was 887,642. It is the 15th most populous city in the U.S., the third-most populous city in the Midwest, after Chicago and Columbus, Ohio, and the fourth-most populous state capital after Phoenix, Arizona, Austin, Texas, and Columbus. The Indianapolis metropolitan area is the 33rd most populous metropolitan statistical area in the U.S., with 2,111,040 residents. Its combined statistical area ranks 28th, with a population of 2,431,361. Indianapolis covers , making it the 18th largest city by land area in the U.S. Indigenous peoples inhabited the area dating to as early as 10,000 BC. In 1818, the Lenape relinquishe ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nuclear War
Nuclear warfare, also known as atomic warfare, is a theoretical military conflict or prepared political strategy that deploys nuclear weaponry. Nuclear weapons are weapons of mass destruction; in contrast to conventional warfare, nuclear warfare can produce destruction in a much shorter time and can have a long-lasting radiological result. A major nuclear exchange would likely have long-term effects, primarily from the fallout released, and could also lead to secondary effects, such as "nuclear winter", nuclear famine and societal collapse. A global thermonuclear war with Cold War-era stockpiles, or even with the current smaller stockpiles, may lead to various scenarios including the extinction of the human race. To date, the only use of nuclear weapons in armed conflict occurred in 1945 with the American atomic bombings of Hiroshima and Nagasaki. On August 6, 1945, a uranium gun-type device (code name "Little Boy") was detonated over the Japanese city of Hiroshima. Thre ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ultimate source o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chromosome
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation. Chromosomes are normally visible under a light microscope only during the metaphase of cell division (where all chromosomes are aligned in the center of the cell in their condensed form). Before this happens, each chromosome is duplicated ( S phase), and both copies are joined by a centromere, resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. The joined copies are now called si ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mendelian Inheritance
Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later popularized by William Bateson. These principles were initially controversial. When Mendel's theories were integrated with the Boveri–Sutton chromosome theory of inheritance by Thomas Hunt Morgan in 1915, they became the core of classical genetics. Ronald Fisher combined these ideas with the theory of natural selection in his 1930 book ''The Genetical Theory of Natural Selection'', putting evolution onto a mathematical footing and forming the basis for population genetics within the modern evolutionary synthesis. History The principles of Mendelian inheritance were named for and first derived by Gregor Johann Mendel, a nineteenth-century Moravian monk who formulated his ideas after conducting simple hybridisation experiments with pea plants (' ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Atheist
Atheism, in the broadest sense, is an absence of belief in the existence of deities. Less broadly, atheism is a rejection of the belief that any deities exist. In an even narrower sense, atheism is specifically the position that there no deities. Atheism is contrasted with theism, which in its most general form is the belief that at least one deity exists. The first individuals to identify themselves as atheists lived in the 18th century during the Age of Enlightenment. The French Revolution, noted for its "unprecedented atheism", witnessed the first significant political movement in history to advocate for the supremacy of human reason.Extract of page 22 In 1967, Albania declared itself the first official atheist cou ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pantheist
Pantheism is the belief that reality, the universe and the cosmos are identical with divinity and a supreme supernatural being or entity, pointing to the universe as being an immanent creator deity still expanding and creating, which has existed since the beginning of time, or that all things compose an all-encompassing, immanent god or goddess and regards the universe as a manifestation of a deity. This includes all astronomical objects being viewed as part of a sole deity. The worship of all gods of every religion is another definition but is more precisely termed Omnism. Pantheist belief does not recognize a distinct personal god, anthropomorphic or otherwise, but instead characterizes a broad range of doctrines differing in forms of relationships between reality and divinity. Pantheistic concepts date back thousands of years, and pantheistic elements have been identified in various religious traditions. The term ''pantheism'' was coined by mathematician Joseph Raphson ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Unitarianism
Unitarianism (from Latin ''unitas'' "unity, oneness", from ''unus'' "one") is a nontrinitarian branch of Christian theology. Most other branches of Christianity and the major Churches accept the doctrine of the Trinity which states that there is one God who exists in three coequal, coeternal, consubstantial divine persons: God the Father, God the Son (Jesus in Christianity, Jesus Christ) and Holy Spirit in Christianity, God the Holy Spirit. Unitarian Christians believe that Jesus was Divine_inspiration, inspired by God in his moral teachings and that he is a Redeemer (Christianity), savior, but not God himself. Unitarianism was established in order to restore "History of Christianity#Early Christianity (c. 31/33–324), primitive Christianity before [what Unitarians saw as] later corruptions setting in"; Unitarians generally reject the doctrine of original sin. The churchmanship of Unitarianism may include liberal denominations or Unitarian Christian denominations that are mo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ursula Le Guin
Ursula Kroeber Le Guin (; October 21, 1929 – January 22, 2018) was an American author best known for her works of speculative fiction, including science fiction works set in her Hainish universe, and the ''Earthsea'' fantasy series. She was first published in 1959, and her literary career spanned nearly sixty years, producing more than twenty novels and over a hundred short stories, in addition to poetry, literary criticism, translations, and children's books. Frequently described as an author of science fiction, Le Guin has also been called a "major voice in American Letters". Le Guin said she would prefer to be known as an "American novelist". Le Guin was born in Berkeley, California, to author Theodora Kroeber and anthropologist Alfred Louis Kroeber. Having earned a master's degree in French, Le Guin began doctoral studies but abandoned these after her marriage in 1953 to historian Charles Le Guin. She began writing full-time in the late 1950s and achieved major critical ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alfred Kroeber
Alfred Louis Kroeber (June 11, 1876 – October 5, 1960) was an American cultural anthropologist. He received his PhD under Franz Boas at Columbia University in 1901, the first doctorate in anthropology awarded by Columbia. He was also the first professor appointed to the Department of Anthropology at the University of California, Berkeley. He played an integral role in the early days of its Museum of Anthropology, where he served as director from 1909 through 1947. Kroeber provided detailed information about Ishi, the last surviving member of the Yahi people, whom he studied over a period of years. He was the father of the acclaimed novelist, poet, and writer of short stories Ursula K. Le Guin. Life Kroeber was born in Hoboken, New Jersey, to parents of German Protestant origin. His mother Johanna Muller was an American of German descent; his father Florence Kroeber came to the United States from Germany at the age of ten, with his parents and family, and became an importer of Fr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Herbert J
Herbert may refer to: People Individuals * Herbert (musician), a pseudonym of Matthew Herbert Name * Herbert (given name) * Herbert (surname) Places Antarctica * Herbert Mountains, Coats Land * Herbert Sound, Graham Land Australia * Herbert, Northern Territory, a rural locality * Herbert, South Australia. former government town * Division of Herbert, an electoral district in Queensland * Herbert River, a river in Queensland * County of Herbert, a cadastral unit in South Australia Canada * Herbert, Saskatchewan, Canada, a town * Herbert Road, St. Albert, Canada New Zealand * Herbert, New Zealand, a town * Mount Herbert (New Zealand) United States * Herbert, Illinois, an unincorporated community * Herbert, Michigan, a former settlement * Herbert Creek, a stream in South Dakota * Herbert Island, Alaska Arts, entertainment, and media Fictional entities * Herbert (Disney character) * Herbert Pocket (''Great Expectations'' character), Pip's close friend and roommate in the Cha ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Spanish And Portuguese Jews
Spanish and Portuguese Jews, also called Western Sephardim, Iberian Jews, or Peninsular Jews, are a distinctive sub-group of Sephardic Jews who are largely descended from Jews who lived as New Christians in the Iberian Peninsula during the immediate generations following the forced expulsion of unconverted Jews Expulsion of the Jews from Spain, from Spain in 1492 and Expulsion of Jews and Muslims from Portugal, from Portugal in 1497. Although the 1492 and 1497 expulsions of unconverted Jews from Spain and Portugal were separate events from the Spanish Inquisition, Spanish and Portuguese Inquisitions (which were established over a decade earlier in 1478), they were ultimately linked, as the Inquisition eventually also led to the fleeing out of Iberia of many descendants of Jewish converts to Catholicism in subsequent generations. Despite the fact that the original Edicts of Expulsion did not apply to Jewish-origin New Christian ''conversos'' —as these were now legally Chris ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |